Description

2-[4-(Prop-2-Yn-1-Yl)Piperazin-1-Yl]Pyrimidine is a high-purity, functionalized heterocyclic compound that serves as a critical building block in advanced organic synthesis. This molecule is valued for its unique piperazine-pyrimidine core and terminal alkyne functionality, which enables versatile chemical modifications, particularly in click chemistry and cross-coupling reactions. It is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Probe Development: The alkyne group facilitates Huisgen 1,3-dipolar cycloaddition (click chemistry) for labeling biomolecules and creating diagnostic probes.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic frameworks.
• Academic & Contract Research: Employed in methodological studies and as a standard in novel synthetic route development.

Basic Information

Product Name	2-[4-(Prop-2-Yn-1-Yl)Piperazin-1-Yl]Pyrimidine
CAS No.	922723-25-9
Molecular Formula	C11H14N4
Molecular Weight	202.26 g/mol
Synonyms	2-(4-Prop-2-yn-1-ylpiperazin-1-yl)pyrimidine; 2-(4-(Prop-2-yn-1-yl)piperazin-1-yl)pyrimidine; 1-(2-Pyrimidinyl)-4-(2-propynyl)piperazine; 4-(2-Propynyl)-1-(2-pyrimidinyl)piperazine; 2-(4-(Prop-2-ynyl)piperazin-1-yl)pyrimidine; 922723-25-9; 2-(4-(Prop-2-yn-1-yl)piperazin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 2-[4-(Prop-2-Yn-1-Yl)Piperazin-1-Yl]Pyrimidine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.