Description

6-(4-Chlorophenyl)-2-[(8-Methoxy-4-Methylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinazoline and pyrimidine-based drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of potential kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• API Development: Employed in the process development and scale-up of potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: May be used as a reference standard or probe in biochemical and cellular assays.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process optimization for the pharmaceutical industry.

Basic Information

Product Name	6-(4-Chlorophenyl)-2-[(8-Methoxy-4-Methylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One
CAS No.	921075-32-3
Molecular Formula	C20H16ClN5O2
Molecular Weight	393.83 g/mol
Synonyms	6-(4-Chlorophenyl)-2-[(8-methoxy-4-methyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone; 2-((8-Methoxy-4-methylquinazolin-2-yl)amino)-6-(4-chlorophenyl)pyrimidin-4(3H)-one; 921075-32-3; 6-(p-Chlorophenyl)-2-[(8-methoxy-4-methylquinazolin-2-yl)amino]pyrimidin-4-ol; UNII-8K1F6S4K6F; 8K1F6S4K6F
EINECS	Contact for details

Quality Control

Our 6-(4-Chlorophenyl)-2-[(8-Methoxy-4-Methylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.