Description

n-[(2-Methylpyrimidin-4-Yl)Methyl]Propan-2-Amine Dihydrochloride Propan-2-Ol is a high-purity chemical intermediate, specifically a dihydrochloride salt solvate, valued for its role in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, where it serves as a key building block for active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily sought by fine chemical manufacturers, contract research organizations (CROs), and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring pyrimidine-based scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for the production of target APIs.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name	n-[(2-Methylpyrimidin-4-Yl)Methyl]Propan-2-Amine Dihydrochloride Propan-2-Ol
CAS No.	921074-75-1
Molecular Formula	C10H19Cl2N3O
Molecular Weight	268.18 g/mol
Synonyms	1-Propan-2-yl-N-[(2-methylpyrimidin-4-yl)methyl]methanamine dihydrochloride; Isopropyl-[(2-methylpyrimidin-4-yl)methyl]amine dihydrochloride propan-2-ol solvate; 2-Methyl-4-[(isopropylamino)methyl]pyrimidine dihydrochloride isopropanolate; N-Isopropyl-1-(2-methylpyrimidin-4-yl)methanamine dihydrochloride isopropanol adduct; (2-Methylpyrimidin-4-yl)methyl(isopropyl)amine dihydrochloride isopropanol solvate; CAS 921074-75-1
EINECS	Contact for details

Quality Control

Our n-[(2-Methylpyrimidin-4-Yl)Methyl]Propan-2-Amine Dihydrochloride Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and conformity to agreed specifications. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We support development and commercial projects with material suitable for research use and can supply grades aligned with current Good Manufacturing Practice (cGMP) principles for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.