Description

Thiazolo[5,4-D]Pyrimidin-2-Amine is a high-purity heterocyclic organic compound belonging to the fused pyrimidine class, serving as a critical advanced pharmaceutical intermediate. Its unique bicyclic structure makes it a valuable scaffold for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in research for creating new fungicides or herbicides due to its bioactive heterocyclic framework.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create complex, high-value specialty chemicals.

Basic Information

Product Name	Thiazolo[5,4-D]Pyrimidin-2-Amine
CAS No.	920313-61-7
Molecular Formula	C5H4N4S
Molecular Weight	152.18 g/mol
Synonyms	2-Aminothiazolo[5,4-d]pyrimidine; Thiazolo[5,4-d]pyrimidin-2-ylamine; 2-Thiazolo[5,4-d]pyrimidinamine; 920313-61-7; Thiazolopyrimidinamine; 2-Amino-7H-thiazolo[5,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our Thiazolo[5,4-D]Pyrimidin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container should be stored in a cool, dry place with minimal exposure to humidity. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.