Description

5-Butyl-2-[(4,7-Dimethylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing next-generation drug candidates where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline and pyrimidine-based active pharmaceutical ingredients (APIs).
• Oncology Research: Serves as a core scaffold for developing small-molecule inhibitors targeting specific kinase pathways involved in cancer cell proliferation.
• Antiviral Drug Development: Used in research programs aimed at creating new antiviral compounds due to its structural similarity to nucleoside analogs.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe to study enzyme function and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• High-Throughput Screening (HTS): Incorporated into compound libraries for screening against novel biological targets to identify lead molecules.

Basic Information

Product Name	5-Butyl-2-[(4,7-Dimethylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4(3H)-One
CAS No.	919721-84-9
Molecular Formula	C19H23N5O
Molecular Weight	337.42 g/mol
Synonyms	5-Butyl-2-[(4,7-dimethyl-2-quinazolinyl)amino]-6-methyl-4(3H)-pyrimidinone; 6-Methyl-5-butyl-2-[(4,7-dimethylquinazolin-2-yl)amino]pyrimidin-4(3H)-one; 919721-84-9; UNII-9I7U3S7W3H; 9I7U3S7W3H; 5-butyl-2-[(4,7-dimethylquinazolin-2-yl)amino]-6-methyl-1H-pyrimidin-4-one; 5-butyl-2-[(4,7-dimethylquinazolin-2-yl)amino]-6-methylpyrimidin-4-ol
EINECS	Contact for details

Quality Control

Every batch of 5-Butyl-2-[(4,7-Dimethylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4(3H)-One is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research. Our products are characterized by advanced techniques including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and away from incompatible materials. For long-term storage, consider inert gas purging to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.