Description

4-Chloro-2-(Methylthio)-5-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. This compound matters for its unique trifluoromethyl and chloro-substituted pyrimidine core, which imparts desirable properties like metabolic stability and lipophilicity to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for functional materials, including liquid crystals and organic electronic components.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-Chloro-2-(Methylthio)-5-(Trifluoromethyl)Pyrimidine
CAS No.	919116-36-2
Molecular Formula	C6H4ClF3N2S
Molecular Weight	228.62 g/mol
Synonyms	4-Chloro-2-(methylsulfanyl)-5-(trifluoromethyl)pyrimidine; 2-Methylthio-4-chloro-5-trifluoromethylpyrimidine; 5-(Trifluoromethyl)-4-chloro-2-(methylthio)pyrimidine; 4-Chloro-2-methylthio-5-trifluoromethylpyrimidine; 919116-36-2; 4-Chloro-2-methylmercapto-5-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Methylthio)-5-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.