Description

Pyrimidine, 2-Chloro-4-(Methylthio)-5-(Trifluoromethyl)- is a specialized halogenated and sulfur-containing pyrimidine derivative, identified by CAS NO 919116-35-1. This compound serves as a high-value synthetic intermediate and building block in advanced organic synthesis, prized for its unique trifluoromethyl and methylthio functional groups. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Research: Serves as a precursor for advanced materials, including liquid crystals and organic semiconductors, due to its electron-deficient aromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for custom synthesis projects and scale-up process development.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	Pyrimidine, 2-Chloro-4-(Methylthio)-5-(Trifluoromethyl)-
CAS No.	919116-35-1
Molecular Formula	C7H4ClF3N2S
Molecular Weight	240.63 g/mol
Synonyms	2-Chloro-4-(methylthio)-5-(trifluoromethyl)pyrimidine; 5-(Trifluoromethyl)-2-chloro-4-methylthiopyrimidine; 2-Chloro-4-methylthio-5-trifluoromethylpyrimidine; 4-Methylthio-2-chloro-5-trifluoromethylpyrimidine; 2-Chloro-4-(methylsulfanyl)-5-(trifluoromethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Methylthio)-5-(Trifluoromethyl)pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure containers are sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.