Description

2-Fluoro-5-Nitro-3-Trifluoromethyl-Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both nitro and trifluoromethyl substituents, makes it a versatile precursor for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity, metabolic stability, and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials, such as fluorinated polymers or small molecules for OLEDs and semiconductors.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags used in bioimaging and studying biological processes.
• Custom Synthesis and R&D: A critical starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Fluoro-5-Nitro-3-Trifluoromethyl-Benzaldehyde
CAS No.	918900-51-3
Molecular Formula	C8H3F4NO3
Molecular Weight	237.11 g/mol
Synonyms	2-Fluoro-5-nitro-α,α,α-trifluoro-m-tolualdehyde; 3-Formyl-2-fluoro-5-nitrobenzotrifluoride; 2-Fluoro-5-nitro-3-(trifluoromethyl)benzaldehyde; 3-(Trifluoromethyl)-2-fluoro-5-nitrobenzaldehyde; 5-Nitro-2-fluoro-3-trifluoromethylbenzaldehyde; Benzaldehyde, 2-fluoro-5-nitro-3-(trifluoromethyl)-; α,α,α-Trifluoro-2-fluoro-5-nitro-m-tolualdehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitro-3-Trifluoromethyl-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.