Description

4-(Benzyloxy)-2,6-Difluorobenzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance and durability.
• Cross-Coupling Reactions: The aldehyde and halogenated aromatic structure make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands and organocatalysts for asymmetric synthesis and fine chemical manufacturing.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to introduce fluorine and aromaticity into polymers, enhancing thermal stability and chemical resistance.

Basic Information

Product Name	4-(Benzyloxy)-2,6-Difluorobenzaldehyde
CAS No.	918524-93-3
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	2,6-Difluoro-4-(phenylmethoxy)benzaldehyde; 4-(Benzyloxy)-2,6-difluorobenzaldehyde; Benzaldehyde, 4-(benzyloxy)-2,6-difluoro-; 2,6-Difluoro-4-(benzyloxy)benzaldehyde; 4-Benzyloxy-2,6-difluorobenzaldehyde; α,2,6-Trifluoro-4-(phenylmethoxy)benzenemethanol (related aldehyde); 918524-93-3
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-2,6-Difluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.