Description

2,5-Difluoro-4-Hydroxybenzaldehyde is a versatile fluorinated aromatic aldehyde building block. This compound matters for its unique molecular structure, which combines a reactive aldehyde group with fluorine substituents and a phenolic hydroxyl group, enabling precise modifications in advanced synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystals used in high-performance displays (LCDs).
• Polymer Modification: Incorporated into specialty polymers to impart specific properties like chemical resistance, thermal stability, or unique optical characteristics.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, Schiff base formation, and other organic transformations to create complex fluorinated molecules.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2,5-Difluoro-4-Hydroxybenzaldehyde
CAS No.	918523-99-6
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	4-Hydroxy-2,5-difluorobenzaldehyde; 2,5-Difluoro-4-hydroxybenzaldehyde; 2,5-Difluoro-4-hydroxy-benzaldehyde; 4-Hydroxy-2,5-difluoro-benzaldehyde; Benzaldehyde, 2,5-difluoro-4-hydroxy-; 2,5-Difluoro-4-hydroxybenzaldehyde (DFHB)
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Hydroxybenzaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.