Description

1-Chloropyrrolo[1,2-C]Pyrimidine is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive chlorinated pyrimidine scaffold, which serves as a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the construction of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials and specialty polymers.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biological target identification.
• Cross-Coupling Reactions: The chlorine atom facilitates Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Nucleophilic Substitution: Acts as an electrophile for reactions with various nucleophiles to introduce diverse functional groups.

Basic Information

Product Name	1-Chloropyrrolo[1,2-C]Pyrimidine
CAS No.	918340-50-8
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	1-Chloro-1H-pyrrolo[1,2-c]pyrimidine; Pyrrolo[1,2-c]pyrimidine, 1-chloro-; 1-Chloro-pyrrolo[1,2-c]pyrimidine; 1-Chloro-1H-pyrrolo[1,2-c]pyrimidine; 1-Chloro-7-azaindole (common name); 1-Chloro-7-azaindole; 1-Cl-7AI; 1-Chloro-7-aza-indole
EINECS	Contact for details

Quality Control

Our 1-Chloropyrrolo[1,2-C]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.