Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Tyr(Ac)-Oh is a specialized, protected amino acid derivative widely used as a critical building block in solid-phase peptide synthesis (SPPS). This compound matters because it provides precise control over the tyrosine residue, preventing unwanted side reactions during the complex assembly of peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who are developing therapeutic peptides, diagnostic agents, and biochemical tools. The product is supplied to exacting standards to ensure consistent performance in sensitive synthetic workflows.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected tyrosine derivative for the controlled, sequential assembly of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs, including hormones, antibiotics, and targeted therapies.
• Bioconjugation: Serves as a modified amino acid for creating peptide-protein or peptide-small molecule conjugates for drug delivery and diagnostics.
• Chemical Biology Probes: Enables the synthesis of labeled or tagged peptides for studying protein-protein interactions and cellular processes.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive peptide leads.
• Academic & Industrial R&D: A fundamental reagent for synthetic chemistry and biochemistry laboratories exploring peptide structure and function.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Tyr(Ac)-Oh
CAS No.	918329-78-9
Molecular Formula	C26H23NO6
Molecular Weight	445.47 g/mol
Synonyms	Fmoc-Tyr(Ac)-OH; N-α-Fmoc-O-acetyl-L-tyrosine; Fmoc-L-Tyrosine(O-acetyl); (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-(4-acetyloxyphenyl)propanoic acid; Fmoc-O-acetyl-L-tyrosine; Fmoc-Tyr(OAc)-OH; N-Fmoc-O-acetyltyrosine; Fmoc-Tyr(Acetyl)-OH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl Tyr(Ac)-Oh is manufactured under strict quality management systems to ensure the high purity and consistency required for sensitive synthetic applications. Each batch is subjected to rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive spectroscopic identification. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.