Description

4,6-Dichloro-5-Iodo-2-(Methylthio)Pyrimidine is a high-value halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antiviral and anticancer drug candidates, leveraging its reactive halogen sites for further functionalization.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the pyrimidine core is a common bioactive motif.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent due to the iodine atom, which can be used for radio-labeling or further coupling reactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4,6-Dichloro-5-Iodo-2-(Methylthio)Pyrimidine
CAS No.	917895-51-3
Molecular Formula	C5H3Cl2IN2S
Molecular Weight	320.96 g/mol
Synonyms	2-(Methylthio)-4,6-dichloro-5-iodopyrimidine; 5-Iodo-4,6-dichloro-2-methylthiopyrimidine; 4,6-Dichloro-5-iodo-2-methylsulfanylpyrimidine; 4,6-Dichloro-5-iodo-2-(methylmercapto)pyrimidine; 917895-51-3; SCHEMBL2180621; AKOS040759232; ZINC000004098756
EINECS	Contact for details

Quality Control

Every batch of 4,6-Dichloro-5-Iodo-2-(Methylthio)Pyrimidine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profile is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.