Description

4-tert-Butyl-n-(4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-3-Yl)Benzamide is a high-purity, advanced pharmaceutical intermediate belonging to the pyridopyrimidinone class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, serving as a key building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Kinase Inhibitor Development: The pyridopyrimidinone core is a privileged structure in the design of protein kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the development of tool compounds for studying specific biological targets and mechanisms.
• Custom Synthesis: Used by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client research programs.

Basic Information

Product Name	4-tert-Butyl-n-(4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-3-Yl)Benzamide
CAS No.	917748-53-9
Molecular Formula	C20H19N3O2
Molecular Weight	333.39 g/mol
Synonyms	4-tert-Butyl-N-(4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)benzamide; 3-[(4-tert-Butylbenzoyl)amino]pyrido[1,2-a]pyrimidin-4-one; 4-tert-Butyl-N-(4-oxopyrido[1,2-a]pyrimidin-3-yl)benzamide; 917748-53-9; 4-tert-Butyl-n-(4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-3-Yl)Benzamide; 4-tert-Butyl-N-(4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-benzamide; Benzamide, 4-(1,1-dimethylethyl)-N-(4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-n-(4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-3-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.