Description

3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-5-Phenyl-Pentanoic Acid is a specialized Fmoc-protected amino acid derivative, a key building block in modern solid-phase peptide synthesis (SPPS). This compound matters for its role in enabling the precise and efficient construction of complex peptide sequences, which are fundamental to pharmaceutical research and development. It is primarily needed by research institutions, pharmaceutical companies, and CROs/CMOs engaged in the discovery and production of peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a critical, protected intermediate for the controlled incorporation of specific amino acid residues into custom peptide chains.
• Pharmaceutical R&D: Used in the research and development of novel peptide drugs, including hormones, enzyme inhibitors, and targeted therapeutics.
• Combinatorial Chemistry Libraries: Serves as a building block for creating diverse peptide libraries used in high-throughput screening for drug discovery.
• Bioconjugation & Probe Development: Employed in the synthesis of peptide tags, fluorescent probes, and other bioconjugates for diagnostic and research applications.
• Academic & Institutional Research: Utilized in biochemistry and molecular biology laboratories for studying protein-protein interactions and enzyme mechanisms.
• Contract Manufacturing: A key raw material for CMOs specializing in the GMP or non-GMP production of peptide active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-5-Phenyl-Pentanoic Acid
CAS No.	917562-05-1
Molecular Formula	C26H25NO4
Molecular Weight	415.48 g/mol
Synonyms	Fmoc-3-amino-5-phenylpentanoic acid; Fmoc-β-homoPhe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-5-phenylpentanoic acid; 3-(Fmoc-amino)-5-phenylpentanoic acid; (3S)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-5-phenylpentanoic acid (for S-isomer); β-Homophenylalanine, N-Fmoc-; Fmoc-β-hPhe-OH; Building block for peptide synthesis
EINECS	Contact for details

Quality Control

Our 3-(9 H-Fluoren-9-Ylmethoxycarbonylamino)-5-Phenyl-Pentanoic Acid is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. We provide comprehensive analytical data, including HPLC purity, chiral purity (where applicable), and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.