Description

Nesfatin-1 (Mouse) is a bioactive peptide hormone derived from the precursor protein nucleobindin-2 (NUCB2). This compound is of significant interest in metabolic and neuroendocrine research due to its role in regulating appetite, energy homeostasis, and stress responses. It is an essential research tool for scientists and pharmaceutical developers in the fields of endocrinology, obesity research, and neuroscience, providing a key reagent for in vitro and in vivo studies targeting metabolic disorders.

Application

• Biomedical Research: Fundamental studies on appetite regulation, energy balance, and the central nervous system's control of metabolism.
• Drug Discovery & Development: Target validation and screening assays for novel therapeutics aimed at treating obesity, diabetes, and eating disorders.
• Endocrinology Studies: Investigation of peptide hormone signaling pathways and their interactions with other metabolic hormones like insulin, leptin, and ghrelin.
• Neuroscience Research: Exploration of Nesfatin-1's role in stress response, anxiety, and depression-related behaviors in preclinical models.
• In Vitro Assays: Used in cell-based studies to examine receptor binding, signal transduction, and gene expression effects.
• Academic & Institutional Research: A critical reagent for universities and research institutes conducting metabolic and physiological studies.

Basic Information

Product Name	Nesfatin-1 (Mouse)
CAS No.	917528-36-0
Molecular Formula	C198H310N56O58S
Molecular Weight	4464.0 g/mol
Synonyms	Mouse Nesfatin-1; NUCB2(1-82) (Mouse); Nucleobindin-2-derived peptide (Mouse); NEFA/NUCB2-derived satiety peptide; NUCB2 Nesfatin-1; Murine Nesfatin-1; Appetite-regulating peptide Nesfatin-1
EINECS	Contact for details

Quality Control

Our Nesfatin-1 (Mouse) is produced under stringent conditions to ensure the highest standards of purity and biological activity. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and endotoxin levels are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Endotoxin Level (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.