Description

4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Benzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound matters as a key building block in the synthesis of targeted kinase inhibitors, offering researchers a reliable and well-characterized starting material for complex molecular architectures. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and inflammatory disease research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent kinase inhibitor drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Contract Manufacturing: Supplied to CDMOs for the production of active pharmaceutical ingredients (APIs) under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for investigating novel signaling pathways and drug mechanisms.

Basic Information

Product Name	4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Benzoic Acid Methyl Ester
CAS No.	917392-54-2
Molecular Formula	C19H18N4O2
Molecular Weight	334.37 g/mol
Synonyms	Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate; 3-((4-(3-Pyridinyl)-2-pyrimidinyl)amino)-4-methylbenzoic acid methyl ester; 917392-54-2; UNII-9Q2F9NQ9TQ; 9Q2F9NQ9TQ; Benzoic acid, 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-, methyl ester; Kinase Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.