Description

Ethyl 2‐(2‐Chloropyrimidin‐5‐Yl)Acetate is a high-purity, versatile pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive chloropyrimidine core with a functionalized ester handle, enabling efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine scaffold.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Material Science: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	Ethyl 2‐(2‐Chloropyrimidin‐5‐Yl)Acetate
CAS No.	917025-00-4
Molecular Formula	C8H9ClN2O2
Molecular Weight	200.62 g/mol
Synonyms	Ethyl (2-chloropyrimidin-5-yl)acetate; 2-(2-Chloro-5-pyrimidinyl)acetic acid ethyl ester; Acetic acid, 2-(2-chloro-5-pyrimidinyl)-, ethyl ester; 5-Pyrimidineacetic acid, 2-chloro-, ethyl ester; 917025-00-4; Ethyl 2-(2-chloropyrimidin-5-yl)acetate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2‐(2‐Chloropyrimidin‐5‐Yl)Acetate is produced under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.