Description

Ethyl 2‐(2‐Bromopyrimidin‐5‐Yl)Acetate is a high-purity brominated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive handle for cross-coupling reactions and further functionalization, enabling the efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed as a monomer or functional unit in the development of organic electronic materials and specialty polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Ethyl 2‐(2‐Bromopyrimidin‐5‐Yl)Acetate
CAS No.	917023-05-3
Molecular Formula	C8H9BrN2O2
Molecular Weight	245.07 g/mol
Synonyms	Ethyl (2-bromopyrimidin-5-yl)acetate; 2-Bromopyrimidin-5-ylacetic Acid Ethyl Ester; Acetic acid, 2-(2-bromopyrimidin-5-yl)-, ethyl ester; 5-(Ethoxycarbonylmethyl)-2-bromopyrimidine; (2-Bromo-5-pyrimidinyl)acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2‐(2‐Bromopyrimidin‐5‐Yl)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.