Description

2-Amino-4-(4-Trifluoromethylphenyl)Pyrimidine is a high-value, fluorinated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and a trifluoromethylphenyl moiety, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and stability.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed as a versatile reagent in cross-coupling reactions and other catalytic processes to introduce complex aromatic systems.
• Life Science Research: Utilized in biochemical research as a scaffold for developing molecular probes and enzyme inhibitors.

Basic Information

Product Name	2-Amino-4-(4-Trifluoromethylphenyl)Pyrimidine
CAS No.	916792-24-0
Molecular Formula	C11H8F3N3
Molecular Weight	239.20 g/mol
Synonyms	2-Amino-4-[4-(trifluoromethyl)phenyl]pyrimidine; 4-(4-Trifluoromethylphenyl)-2-pyrimidinamine; 2-Pyrimidinamine, 4-[4-(trifluoromethyl)phenyl]-; 2-Amino-4-(alpha,alpha,α-trifluoro-p-tolyl)pyrimidine; 4-(4-Trifluoromethylphenyl)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Trifluoromethylphenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.