Description

[1-(4-Trifluoromethyl-Pyrimidin-2-Yl)-Piperidin-3-Yl]-Methanol is a high-purity (98+%) organic building block with the molecular formula C11H14F3N3O and a molecular weight of 261.24. This compound is a critical intermediate valued for its piperidine-pyrimidine core and trifluoromethyl group, which are key motifs in modern medicinal chemistry. It is primarily utilized by research and development organizations in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular tools to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized scaffold.
• Academic & Institutional Research: Used in universities and research institutes for exploratory chemistry and methodology development in heterocyclic chemistry.

Basic Information

Product Name	[1-(4-Trifluoromethyl-Pyrimidin-2-Yl)-Piperidin-3-Yl]-Methanol
CAS No.	916791-20-3
Molecular Formula	C11H14F3N3O
Molecular Weight	261.24 g/mol
Synonyms	3-(Hydroxymethyl)-1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidine; 1-[4-(Trifluoromethyl)pyrimidin-2-yl]piperidin-3-ylmethanol; (1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-3-yl)methanol; 2-(3-(Hydroxymethyl)piperidin-1-yl)-4-(trifluoromethyl)pyrimidine; 916791-20-3; 1-(4-Trifluoromethyl-2-pyrimidinyl)-3-piperidinemethanol
EINECS	Contact for details

Quality Control

Our [1-(4-Trifluoromethyl-Pyrimidin-2-Yl)-Piperidin-3-Yl]-Methanol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by HPLC, NMR, and mass spectrometry. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.