Description

(4-Chloro-Pyrimidin-2-Yl)-Piperidin-4-Ylmethyl-Amine is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific molecular architecture enables precise structural modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific pyrimidine-based structures.
• Chemical Biology: Serves as a versatile building block for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Potential precursor for the synthesis of specialized ligands and functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process optimization for client projects.

Basic Information

Product Name	(4-Chloro-Pyrimidin-2-Yl)-Piperidin-4-Ylmethyl-Amine
CAS No.	916791-16-7
Molecular Formula	C10H15ClN4
Molecular Weight	226.71 g/mol
Synonyms	4-[(4-Chloro-2-pyrimidinyl)amino]methyl]piperidine; 1-[(4-Chloro-2-pyrimidinyl)amino]methyl]-4-piperidinamine; 4-((4-Chloropyrimidin-2-yl)amino)methyl)piperidine; (4-Chloro-2-pyrimidinyl)-(4-piperidinylmethyl)amine; 4-Chloro-N-[(4-piperidinyl)methyl]-2-pyrimidinamine; 916791-16-7; 4-[(4-Chloro-2-pyrimidinyl)amino]methyl]piperidine (main IUPAC-style name)
EINECS	Contact for details

Quality Control

Our (4-Chloro-Pyrimidin-2-Yl)-Piperidin-4-Ylmethyl-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.