Description

1-(4-Chloro-2-Pyrimidinyl)-4-Piperidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research and development chemists and manufacturers in the pharmaceutical and biotechnology sectors working on innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• API Development: Serves as a core scaffold for constructing final active pharmaceutical ingredients in pilot and commercial-scale production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays and proteomics research.

Basic Information

Product Name	1-(4-Chloro-2-Pyrimidinyl)-4-Piperidinecarboxylic Acid
CAS No.	916791-12-3
Molecular Formula	C10H10ClN3O2
Molecular Weight	239.66 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(4-chloro-2-pyrimidinyl)-; 1-(4-Chloropyrimidin-2-yl)piperidine-4-carboxylic acid; 4-Carboxy-1-(4-chloro-2-pyrimidinyl)piperidine; 1-(4-Chloro-pyrimidin-2-yl)-piperidine-4-carboxylic acid; 916791-12-3; UNII-7D4J3F8Q5R
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-2-Pyrimidinyl)-4-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.