Description

Pentafluorophenyl 1-Thieno[3,2-D]Pyrimidin-4-Ylpiperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in kinase inhibitor programs. It is essential for pharmaceutical companies, biotechnology firms, and academic research institutions focused on developing new treatments for oncology and other disease areas. Our supply ensures consistent quality and reliable availability for your most demanding synthesis projects.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology research.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Biochemical Research: Employed as a tool compound or ligand in enzyme inhibition assays and biological target validation.
• Custom Synthesis: Serves as a specialized starting material for contract research organizations (CROs) and custom synthesis providers.
• Academic Research: Utilized in university laboratories for investigating new chemical entities and their biological activities.

Basic Information

Product Name	Pentafluorophenyl 1-Thieno[3,2-D]Pyrimidin-4-Ylpiperidine-4-Carboxylate
CAS No.	916766-92-2
Molecular Formula	C20H13F5N3O2S
Molecular Weight	466.40 g/mol
Synonyms	Pentafluorophenyl 4-(thieno[3,2-d]pyrimidin-4-yl)piperidine-1-carboxylate; 1-[(2,3,4,5,6-Pentafluorophenyl)carbonyl]-4-(thieno[3,2-d]pyrimidin-4-yl)piperidine; 4-(Thieno[3,2-d]pyrimidin-4-yl)piperidine-1-carboxylic acid pentafluorophenyl ester; CAS 916766-92-2; Thienopyrimidine-piperidine carboxylate derivative; Kinase inhibitor intermediate PFPP-TPP
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 1-Thieno[3,2-D]Pyrimidin-4-Ylpiperidine-4-Carboxylate is manufactured under strict quality control protocols to meet the exacting standards of pharmaceutical development. Each batch is analyzed using advanced techniques like HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all critical specifications. We adhere to cGMP principles where applicable to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.