Description

1-(Thieno[3,2-D]Pyrimidin-4-Yl)Piperidine-4-Carboxaldehyde is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures with targeted biological activity. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Core scaffold for the construction of potential kinase inhibitors, a major class of targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to improve drug potency and selectivity.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study specific biological pathways and protein functions.
• Custom Synthesis: Basis for contract research organizations (CROs) and CDMOs to produce bespoke compounds for client drug discovery projects.

Basic Information

Product Name	1-(Thieno[3,2-D]Pyrimidin-4-Yl)Piperidine-4-Carboxaldehyde
CAS No.	916766-91-1
Molecular Formula	C12H13N3OS
Molecular Weight	247.31 g/mol
Synonyms	4-Piperidinecarboxaldehyde, 1-(thieno[3,2-d]pyrimidin-4-yl)-; 1-(Thieno[3,2-d]pyrimidin-4-yl)piperidine-4-carbaldehyde; 1-(Thieno[3,2-d]pyrimidin-4-yl)-4-piperidinecarboxaldehyde; 916766-91-1; 1-(Thieno[3,2-d]pyrimidin-4-yl)piperidine-4-carboxaldehyde; 4-Piperidinecarboxaldehyde, 1-(thieno[3,2-d]pyrimidin-4-yl)- (9CI); 1-(Thieno[3,2-d]pyrimidin-4-yl)piperidine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(Thieno[3,2-D]Pyrimidin-4-Yl)Piperidine-4-Carboxaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ICH guidelines for impurity identification and control, providing the traceability and documentation required for preclinical and early-phase clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and should be handled under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.