Description

6-Chloro-1-[(4-Methoxyphenyl)Methyl]-3-Methyl-2,4(1H,3H)-Pyrimidinedione is a high-purity, synthetically derived pyrimidinedione derivative, serving as a critical pharmaceutical intermediate and research chemical. Its value lies in its specific molecular architecture, which is essential for the synthesis of more complex active pharmaceutical ingredients (APIs) and for probing biological pathways in medicinal chemistry research. This compound is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of proprietary drug candidates, particularly in central nervous system (CNS) and antiviral research areas.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Biochemical Tool Compound: Employed in vitro and in vivo to study enzyme inhibition, receptor binding, and other specific biological mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing reaction conditions for cost-effective API manufacturing.
• Academic Research: A valuable reagent for universities and institutes conducting fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Chloro-1-[(4-Methoxyphenyl)Methyl]-3-Methyl-2,4(1H,3H)-Pyrimidinedione
CAS No.	916764-89-1
Molecular Formula	C₁₃H₁₃ClN₂O₃
Molecular Weight	280.71 g/mol
Synonyms	6-Chloro-1-(4-methoxybenzyl)-3-methylpyrimidine-2,4(1H,3H)-dione; 6-Chloro-1-(4-methoxybenzyl)-3-methyluracil; 1-(4-Methoxybenzyl)-6-chloro-3-methyluracil; 6-Chloro-3-methyl-1-[(4-methoxyphenyl)methyl]uracil; 916764-89-1; 6-Chloro-1-(p-methoxybenzyl)-3-methyluracil
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-[(4-Methoxyphenyl)Methyl]-3-Methyl-2,4(1H,3H)-Pyrimidinedione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), identity confirmation, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.