Description

Benzenemethanamine, 2,3,4,5,6-Pentafluoro-A-Methyl-, (As)- is a specialized fluorinated aromatic amine building block of significant interest in advanced chemical synthesis. Its core value lies in the unique combination of a reactive amine group and a perfluorinated benzene ring, enabling the precise introduction of fluorine atoms to modulate the properties of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where fluorine substitution improves environmental stability and efficacy.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporation into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for fluorine-18 labeled radiopharmaceuticals for medical imaging.
• Organic Synthesis & Catalysis: Valuable ligand or precursor in asymmetric catalysis and the preparation of complex fluorinated organic molecules.

Basic Information

Product Name	Benzenemethanamine, 2,3,4,5,6-Pentafluoro-A-Methyl-, (As)-
CAS No.	916675-98-4
Molecular Formula	C8H6F5N
Molecular Weight	211.13 g/mol
Synonyms	(αS)-α-Methyl-2,3,4,5,6-pentafluorobenzylamine; (S)-1-(2,3,4,5,6-Pentafluorophenyl)ethan-1-amine; (S)-α-Methyl-2,3,4,5,6-pentafluorobenzylamine; Pentafluorobenzylamine, α-methyl-, (S)-; (S)-Pentafluoro-α-methylbenzylamine; (S)-1-(Pentafluorophenyl)ethylamine; (S)-2,3,4,5,6-Pentafluoro-α-methylbenzylamine; (S)-1-Amino-1-(2,3,4,5,6-pentafluorophenyl)ethane
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, 2,3,4,5,6-Pentafluoro-A-Methyl-, (As)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure compliance with exacting customer specifications for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to minimize oxidation and moisture uptake. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual ≤ 0.5%, Total ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.