Description

N2-[4-(Aminomethyl)Phenyl]-5-Fluoro-N4-Phenylpyrimidine-2,4-Diamine is a high-purity, functionalized pyrimidine derivative designed for advanced research and pharmaceutical development. This compound serves as a critical building block and pharmacophore in the synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is essential for medicinal chemists and process R&D teams in pharmaceutical, biotechnology, and fine chemical industries seeking to develop next-generation small molecule inhibitors.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile aminomethyl and fluoropyrimidine motifs.
• Biochemical Probe Development: Serves as a core scaffold for creating molecular probes to study enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses serving the pharmaceutical and agrochemical sectors.
• Academic Research: Utilized in universities and research institutes for pioneering studies in heterocyclic chemistry and drug design.

Basic Information

Product Name	N2-[4-(Aminomethyl)Phenyl]-5-Fluoro-N4-Phenylpyrimidine-2,4-Diamine
CAS No.	916603-07-1
Molecular Formula	C17H16FN5
Molecular Weight	309.34 g/mol
Synonyms	5-Fluoro-N2-[4-(aminomethyl)phenyl]-N4-phenyl-2,4-pyrimidinediamine; 2,4-Pyrimidinediamine, 5-fluoro-N2-[4-(aminomethyl)phenyl]-N4-phenyl-; 916603-07-1; 5-Fluoro-N4-phenyl-N2-(4-(aminomethyl)phenyl)pyrimidine-2,4-diamine; N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our N2-[4-(Aminomethyl)Phenyl]-5-Fluoro-N4-Phenylpyrimidine-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure compliance with exacting research-grade and GMP-starting material standards. Comprehensive Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.