Description

4-Methoxy-2-(trifluoromethyl)benzylamine is a high-value aromatic amine building block featuring a methoxy group and a trifluoromethyl substituent on the benzene ring. This unique structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and agrochemicals, where the trifluoromethyl group is prized for its ability to enhance metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials, host materials, and other functional components in electronic displays and lighting.
• Organic Synthesis & Catalysis: Employed as a versatile amine component in coupling reactions (e.g., Buchwald-Hartwig amination) and for the preparation of ligands in catalytic systems.
• Fluorinated Polymer Precursor: Acts as a monomer or modifier in the synthesis of specialty polymers with enhanced chemical resistance and thermal stability.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Benzylamine
CAS No.	916420-84-3
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	2-(Trifluoromethyl)-4-methoxybenzylamine; 4-Methoxy-α-(trifluoromethyl)benzenemethanamine; (4-Methoxy-2-(trifluoromethyl)phenyl)methanamine; 1-(4-Methoxy-2-(trifluoromethyl)phenyl)methanamine; α-(Trifluoromethyl)-4-methoxybenzylamine; 4-Methoxy-2-trifluoromethylbenzylamine; 2-Trifluoromethyl-4-methoxybenzylamine; Benzenemethanamine, 4-methoxy-α-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(trifluoromethyl)benzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.