Description

3-Fluoro-2-Methoxybenzylamine is a versatile fluorinated aromatic amine building block of significant importance in modern synthetic chemistry. Its molecular structure, featuring both fluorine and methoxy substituents adjacent to a reactive benzylamine group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties and intermolecular interactions.
• Chemical Biology & Proteomics: Utilized as a building block for designing molecular probes, fluorescent tags, and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Fluoro-2-Methoxybenzylamine
CAS No.	916420-49-0
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	(3-Fluoro-2-methoxyphenyl)methanamine; 1-(3-Fluoro-2-methoxyphenyl)methanamine; 2-Methoxy-3-fluorobenzylamine; Benzenemethanamine, 3-fluoro-2-methoxy-; 3-Fluoro-2-methoxybenzenemethanamine; 3-Fluoro-o-anisylamine; α-Amino-3-fluoro-2-methoxytoluene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methoxybenzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.