Description

2-Chloro-4,6-Bis(trifluoromethyl)benzaldehyde is a high-value fluorinated aromatic aldehyde building block, distinguished by its unique substitution pattern. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its trifluoromethyl and aldehyde groups enable precise molecular modifications. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Organic Electronic Materials: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Custom Fluorination Chemistry: Provides a versatile starting point for further functionalization and introduction of complex fluorinated groups into target molecules.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	2-Chloro-4,6-Bis(trifluoromethyl)benzaldehyde
CAS No.	916420-48-9
Molecular Formula	C9H3ClF6O
Molecular Weight	276.56 g/mol
Synonyms	2-Chloro-α,α,α,α',α',α'-hexafluoro-4,6-xylene-α-carboxaldehyde; 2-Chloro-4,6-bis(trifluoromethyl)benzenecarboxaldehyde; 4,6-Bis(trifluoromethyl)-2-chlorobenzaldehyde; 2-Chloro-4,6-di(trifluoromethyl)benzaldehyde; 2-Chloro-α,α,α,α',α',α'-hexafluoro-p-xylene-α-carboxaldehyde; Benzaldehyde, 2-chloro-4,6-bis(trifluoromethyl)-; 916420-48-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,6-Bis(trifluoromethyl)benzaldehyde is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.