Description

Methyl 5-Fluoro-6-Methylpyrimidine-4-Carboxylate CAS NO 916213-46-2 is a high-purity fluorinated pyrimidine derivative, a critical building block in advanced organic synthesis. Its value lies in its precise molecular structure, which enables the construction of complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in oncology, antiviral, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors to study biological pathways and protein function.
• Material Science Research: Investigated as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its rigid, heterocyclic core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity fluorinated heterocycles.

Basic Information

Product Name	Methyl 5-Fluoro-6-Methylpyrimidine-4-Carboxylate
CAS No.	916213-46-2
Molecular Formula	C7H7FN2O2
Molecular Weight	170.14 g/mol
Synonyms	Methyl 5-fluoro-6-methyl-4-pyrimidinecarboxylate; 5-Fluoro-6-methylpyrimidine-4-carboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 5-fluoro-6-methyl-, methyl ester; 916213-46-2; Methyl 5-fluoro-6-methyl-1,3-diazine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluoro-6-Methylpyrimidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.