Description

Biotin-X Cadaverine [5-(((n-(Biotinoyl)Amino)Hexanoyl)Amino)Pentylamine, Trifluoroacetic Acid Salt] is a high-purity, heterobifunctional crosslinking reagent that combines the strong binding affinity of biotin with a reactive primary amine group via an extended spacer arm. This compound is essential for researchers and manufacturers requiring precise and stable conjugation of biomolecules, such as proteins and nucleic acids, to avidin or streptavidin-based detection systems. It is a critical tool for professionals in bioconjugation, diagnostic assay development, and advanced life science research, where reliable and specific labeling is paramount. The product is supplied as the trifluoroacetic acid salt to enhance stability and solubility.

Application

• Bioconjugation and Labeling: Primary amine-reactive reagent for introducing biotin tags onto antibodies, enzymes, peptides, and other biomolecules for detection and purification.
• Diagnostic Assay Development: Used to create biotinylated probes and components for ELISA, lateral flow assays, and other immunoassay platforms.
• Affinity Chromatography: Preparation of biotinylated ligands for immobilization onto streptavidin-coated resins or surfaces.
• Cell Surface Labeling: Modification of cell surface proteins or amines for tracking and isolation studies using flow cytometry or microscopy.
• Protein-Protein Interaction Studies: Facilitates crosslinking and pull-down experiments to study protein complexes.
• Microarray and Biosensor Fabrication: Functionalization of surfaces with biotin for creating patterned arrays and sensitive detection layers.
• Drug Delivery System Research: Conjugation of targeting ligands to drug carriers via the amine-reactive group.
• Next-Generation Sequencing (NGS): Preparation of biotinylated adapters or primers for target capture and library preparation.

Basic Information

Product Name	Biotin-X Cadaverine [5-(((n-(Biotinoyl)Amino)Hexanoyl)Amino)Pentylamine, Trifluoroacetic Acid Salt]
CAS No.	916165-67-8
Molecular Formula	C26H47N7O4S • C2HF3O2
Molecular Weight	Contact for details
Synonyms	Biotin-X-Cadaverine; Biotinamidocaproylcadaverine; 5-((6-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)pentylamine TFA salt; N-Biotinyl-6-aminohexanoyl-1,5-diaminopentane TFA salt; Biotin-XX Cadaverine (alternative nomenclature); Biotin-LC-Cadaverine; (+)-Biotinyl-6-aminocaproyl-1,5-diaminopentane trifluoroacetate; Biotinamidohexanoylcadaverine
EINECS	Contact for details

Quality Control

Our Biotin-X Cadaverine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for sensitive life science applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We adhere to relevant industry guidelines to support our customers' compliance needs in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.