Description

Carbamic Acid, n-[(1S)-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-(Hydroxymethyl)Propyl]-, 9H-Fluoren-9-Ylmethyl Ester is a sophisticated, optically active building block designed for advanced organic synthesis. This compound is critical for the controlled introduction of protected amino acid functionalities in complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid derivative for the sequential assembly of custom peptides.
• Pharmaceutical Intermediate: Used in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for metabolic and neurological targets.
• Peptidomimetic Development: Acts as a crucial scaffold for creating stable, drug-like molecules that mimic natural peptides.
• Bioconjugation Chemistry: Enables the site-specific labeling or functionalization of proteins and other biomolecules.
• Combinatorial Chemistry Libraries: Provides a versatile building block for generating diverse compound libraries for high-throughput screening.
• Academic & Industrial Research: Supports fundamental research in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Carbamic Acid, n-[(1S)-3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-(Hydroxymethyl)Propyl]-, 9H-Fluoren-9-Ylmethyl Ester
CAS No.	915714-21-5
Molecular Formula	C24H28N2O5
Molecular Weight	424.49 g/mol
Synonyms	Fmoc-Lys(Boc)-OH; Fmoc-L-lysine(Boc)-OH; N6-Boc-Nα-Fmoc-L-lysine; Nα-(9-Fluorenylmethoxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; Fmoc-Lys(Boc)-OH; Boc-Lys(Fmoc)-OH; Nα-Fmoc-Nε-Boc-L-lysine
EINECS	Contact for details

Quality Control

Our production of this high-value building block adheres to stringent quality protocols. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a controlled environment to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.