Description

D-Serine, n-Methyl- CAS NO 915405-01-5 is a high-purity, non-natural amino acid derivative, specifically an N-methylated analog of D-serine. This compound is a critical chiral building block and research chemical, valued for its role in modulating N-methyl-D-aspartate (NMDA) receptor function in neurological studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers developing novel therapeutics, diagnostic agents, and advanced biochemical tools.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel neuroactive compounds and potential drug candidates targeting the central nervous system.
• Biochemical Research: Used as a selective tool compound in neuroscience to study NMDA receptor pharmacology, synaptic plasticity, and mechanisms related to memory and learning.
• Peptide Synthesis: Serves as a specialized, protected amino acid building block for the solid-phase or solution-phase synthesis of modified peptides with enhanced stability or specific biological activity.
• Reference Standard: Employed as an analytical standard in HPLC, LC-MS, or NMR for method development, validation, and quality control in pharmaceutical analysis.
• Fine Chemical Intermediate: Used in the multi-step synthesis of complex organic molecules for agrochemicals, specialty materials, and other advanced chemical applications.

Basic Information

Product Name	D-Serine, n-Methyl-
CAS No.	915405-01-5
Molecular Formula	C₄H₉NO₃
Molecular Weight	119.12 g/mol
Synonyms	(R)-2-Amino-3-methoxypropanoic acid; N-Methyl-D-serine; D-N-Methylserine; (R)-2-(Methylamino)-3-hydroxypropanoic acid; Methyl-D-serine; D-3-Hydroxy-2-(methylamino)propionic acid
EINECS	Contact for details

Quality Control

Our D-Serine, n-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.