Description

8-Trifluoromethyl-Quinazoline-2,4-Diamine is a high-purity, specialized quinazoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical agents and agrochemicals, offering a unique trifluoromethylated scaffold. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, drug discovery, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Organic Synthesis: Employed in advanced organic reactions to introduce the quinazoline-2,4-diamine moiety into complex molecular architectures.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique electronic or thermal properties.

Basic Information

Product Name	8-Trifluoromethyl-Quinazoline-2,4-Diamine
CAS No.	915402-37-8
Molecular Formula	C9H7F3N4
Molecular Weight	228.18 g/mol
Synonyms	2,4-Diamino-8-(trifluoromethyl)quinazoline; 8-(Trifluoromethyl)quinazoline-2,4-diamine; Quinazoline-2,4-diamine, 8-(trifluoromethyl)-; 2,4-Quinazolinediamine, 8-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 8-Trifluoromethyl-Quinazoline-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.