Description

4-Ethyl-2-Trifluoromethyl-Pyrimidine-5-Carboxylic Acid is a high-value, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a trifluoromethyl group, makes it an essential intermediate for creating novel compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at research and development teams within the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating chemical probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Ethyl-2-Trifluoromethyl-Pyrimidine-5-Carboxylic Acid
CAS No.	915376-41-9
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	4-Ethyl-2-(trifluoromethyl)pyrimidine-5-carboxylic acid; 5-Pyrimidinecarboxylic acid, 4-ethyl-2-(trifluoromethyl)-; 2-Trifluoromethyl-4-ethyl-pyrimidine-5-carboxylic acid; 4-Ethyl-2-trifluoromethyl-5-pyrimidinecarboxylic acid; 915376-41-9; 4-Ethyl-2-(trifluoromethyl)-5-pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Ethyl-2-Trifluoromethyl-Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For projects requiring specific regulatory support, we can discuss documentation aligned with cGMP or other relevant quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.