Description

Pyrido[4,3-D]Pyrimidine, 7-Chloro-4-(4-Morpholinyl)- is a high-value heterocyclic organic compound featuring a fused pyrido-pyrimidine core substituted with chloro and morpholinyl functional groups. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs). The compound's defined structure enables precise targeting in drug discovery programs, particularly in kinase inhibitor development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and exploring new chemical entities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and development services.

Basic Information

Product Name	Pyrido[4,3-D]Pyrimidine, 7-Chloro-4-(4-Morpholinyl)-
CAS No.	915190-39-5
Molecular Formula	C11H11ClN4O
Molecular Weight	250.68 g/mol
Synonyms	7-Chloro-4-morpholinopyrido[4,3-d]pyrimidine; 4-(7-Chloropyrido[4,3-d]pyrimidin-4-yl)morpholine; 7-Chloro-4-morpholino-4H-pyrido[4,3-d]pyrimidine; 4-(7-Chloro-4H-pyrido[4,3-d]pyrimidin-4-yl)morpholine; 7-Chloro-4-(morpholin-4-yl)pyrido[4,3-d]pyrimidine; 915190-39-5; 7-Chloro-4-morpholin-4-yl-pyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrido[4,3-D]Pyrimidine, 7-Chloro-4-(4-Morpholinyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical methods is provided with each shipment. We support development under quality systems suitable for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize moisture exposure. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.