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Ethyl 7H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate CAS NO 915142-91-5


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CAS No.:915142-91-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 7H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate is a high-purity, heterocyclic organic building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the construction of complex molecules, particularly in the field of kinase inhibitor discovery and medicinal chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule therapeutics.
  • Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • Biochemical Tool Compound Synthesis: Employed in the creation of probes and inhibitors for studying specific biological pathways and enzyme functions.
  • Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic compounds in custom synthesis and contract manufacturing.
  • Academic Research: Utilized in university and institutional labs for methodological development and the exploration of new chemical reactions involving fused pyrimidine systems.

Basic Information

Item Detail
Product Name Ethyl 7H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate
CAS No. 915142-91-5
Molecular Formula C9H9N3O2
Molecular Weight 191.19 g/mol
Synonyms Ethyl 7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate; 4-Pyrimidinecarboxylic acid, 7H-pyrrolo[2,3-d]pyrimidin-4-yl, ethyl ester; 7H-Pyrrolo[2,3-d]pyrimidine-4-carboxylic acid ethyl ester; Ethyl 7-azaindole-4-carboxylate (related structural name); Pyrrolopyrimidine carboxylate ester; Aza-indole derivative; Kinase inhibitor intermediate; Heterocyclic building block
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Quality Control

Our Ethyl 7H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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