Description

(R)-4-Hydroxy-4-Methyl-Orn(Fitc)7-Phalloidin is a highly specialized, fluorescently labeled derivative of the potent actin-binding toxin, phalloidin. This compound matters for researchers requiring precise, high-contrast visualization of filamentous actin (F-actin) structures in fixed cells and tissues. It is an essential tool for scientists in cell biology, neuroscience, and toxicology who need reliable, specific probes for cytoskeletal studies.

Application

• Fluorescence Microscopy: Primary application for labeling and visualizing F-actin networks in fixed cell specimens.
• Cytoskeleton Research: Used to study actin dynamics, cell morphology, and structural changes during processes like cell division or migration.
• Neuroscience Studies: Employed to examine actin distribution in neurons, including growth cones, synapses, and dendritic spines.
• High-Content Screening (HCS): Acts as a key fluorescent probe in automated imaging systems for drug discovery and toxicology assays.
• Diagnostic Pathology: Can be used in research settings to visualize actin-rich structures in tissue sections, aiding in morphological analysis.
• Pharmaceutical Development: Serves as a tool in mechanistic studies of compounds that affect the cytoskeleton.

Basic Information

Product Name	(R)-4-Hydroxy-4-Methyl-Orn(Fitc)7-Phalloidin
CAS No.	915026-99-2
Molecular Formula	C₆₈H₈₀N₁₂O₁₈S₂
Molecular Weight	~1401.6 g/mol
Synonyms	FITC-Phalloidin; Fluorescein Isothiocyanate Labeled Phalloidin; Phalloidin-FITC; Phalloidin, FITC conjugate; (R)-4-Hydroxy-4-methylornithine(FITC)7-phalloidin; Actin-Tracker Green; F-actin staining probe, FITC conjugate
EINECS	Contact for details

Quality Control

Our (R)-4-Hydroxy-4-Methyl-Orn(Fitc)7-Phalloidin is produced and tested to meet the stringent requirements of life science research. Each batch undergoes rigorous analytical characterization to ensure high purity, specific labeling, and optimal performance in fluorescence applications. Certificates of Analysis (COA) detailing purity, fluorescence properties, and functional performance data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Solutions prepared from this product should be aliquoted and stored frozen, avoiding repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Yellow to orange solid or lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Extinction Coefficient (ε)	~68,000 cm⁻¹M⁻¹ at 494 nm
Excitation/Emission Maxima	~494 nm / ~518 nm
Solubility	Soluble in DMSO, methanol, or aqueous buffers
Functional Activity	Binds specifically to F-actin; suitable for microscopy

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.