Description

7-Aminoactinomycin D is a vital fluorescent dye and biochemical probe derived from actinomycin D. This compound is essential for its high-affinity binding to double-stranded DNA, enabling critical research in cell biology and molecular diagnostics. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and life science sectors for applications such as cell viability assays and chromosome staining.

Application

• Flow Cytometry: Used as a fluorescent stain for dead cell discrimination in multi-parameter flow cytometry assays.
• Cell Viability Assays: A key component in assays to distinguish between live and dead cells based on membrane integrity.
• Fluorescence Microscopy: Employed for nuclear staining and chromosome visualization in fixed-cell imaging.
• Apoptosis Detection: Utilized in research to identify and study programmed cell death pathways.
• DNA Binding Studies: Serves as a tool compound in biochemical research to investigate DNA intercalation and groove binding.
• Research Reagent: A critical raw material in the formulation of diagnostic kits and research-grade biochemicals.

Basic Information

Product Name	7-Aminoactinomycin D
CAS No.	7240-37-1
Molecular Formula	C62H86N12O16
Molecular Weight	1279.44 g/mol
Synonyms	7-AAD; 7-Aminoactinomycin D; 7-Amino-AMD; 7-Aminoactinomycin; NSC 653284; Actinomycin D, 7-amino-; 7-Amino-actinomycin D; 7-Amino-actinomycin
EINECS	Contact for details

Quality Control

Our 7-Aminoactinomycin D is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in relevant assays. We adhere to ISO 9001 quality management principles, and the product meets specifications for use as a high-grade biochemical reagent.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is strictly light-sensitive and must be protected from all light exposure during storage and handling to maintain stability and performance.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Fluorescence Performance	Conforms to functional assay
Solubility	Soluble in DMSO, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.