Description

3-Fluoro-5-Methoxybenzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the synergistic reactivity of the benzyl alcohol group and the strategic positioning of the fluorine and methoxy substituents on the benzene ring, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The benzyl alcohol moiety can be functionalized or used in palladium-catalyzed coupling reactions to create complex biaryl structures.
• Protecting Group Chemistry: Utilized in multi-step synthetic routes where the alcohol group requires temporary protection and subsequent deprotection.
• Fluorine-18 Radiochemistry: Potential precursor for the synthesis of PET (Positron Emission Tomography) tracers in medical imaging.

Basic Information

Product Name	3-Fluoro-5-Methoxybenzyl Alcohol
CAS No.	914637-27-7
Molecular Formula	C8H9FO2
Molecular Weight	156.15 g/mol
Synonyms	(3-Fluoro-5-methoxyphenyl)methanol; 3-Fluoro-5-methoxybenzenemethanol; 1-(3-Fluoro-5-methoxyphenyl)methanol; 3-Fluoro-5-methoxy-benzylalcohol; 3-Fluoro-5-methoxybenzylalcohol; 3-Fluoro-5-methoxy benzyl alcohol; 3-Fluoro-5-methoxy phenyl methanol
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methoxybenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.