Description

6-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily utilized by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers targeting oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel kinase inhibitors and other targeted therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of investigational and commercial drugs.
• Biochemical Research: Serves as a tool compound for studying enzymatic pathways and biological target interactions.
• Custom Synthesis: Basis for producing derivatives and analogs for specialized client projects.

Basic Information

Product Name	6-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine
CAS No.	914612-23-0
Molecular Formula	C16H16ClN3
Molecular Weight	285.77 g/mol
Synonyms	4-Chloro-6-benzyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; Pyrido[4,3-d]pyrimidine, 6-benzyl-4-chloro-5,6,7,8-tetrahydro-; 914612-23-0; 6-Benzyl-4-chloro-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; 4-Chloro-6-benzyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 6-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and current industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.