Description

4-Chloro-2-Methyl-6-(Pyrrolidin-1-Yl)Pyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the introduction of key structural motifs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or functional materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.

Basic Information

Product Name	4-Chloro-2-Methyl-6-(Pyrrolidin-1-Yl)Pyrimidine
CAS No.	914349-69-2
Molecular Formula	C9H12ClN3
Molecular Weight	197.66 g/mol
Synonyms	4-Chloro-2-methyl-6-(1-pyrrolidinyl)pyrimidine; 6-(Pyrrolidin-1-yl)-4-chloro-2-methylpyrimidine; 2-Methyl-4-chloro-6-pyrrolidin-1-ylpyrimidine; 4-Chloro-2-methyl-6-pyrrolidin-1-yl-pyrimidine; 914349-69-2; 4-Chloro-2-methyl-6-(pyrrolidin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-6-(Pyrrolidin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.