Description

3-(2-Aminopyrimidin-5-Yl)Benzoic Acid is a high-purity, bifunctional organic building block that combines a benzoic acid moiety with an aminopyrimidine group. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where it serves as a key intermediate. It is primarily utilized by medicinal chemists and process development scientists in the life sciences industry for creating targeted active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme function and cellular signaling pathways.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and herbicides.
• Material Science: Potential monomer or linker for constructing functional polymers and metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	3-(2-Aminopyrimidin-5-Yl)Benzoic Acid
CAS No.	914349-45-4
Molecular Formula	C11H9N3O2
Molecular Weight	215.21 g/mol
Synonyms	5-(3-Carboxyphenyl)pyrimidin-2-amine; 3-(2-Amino-5-pyrimidinyl)benzoic acid; Benzoic acid, 3-(2-amino-5-pyrimidinyl)-; 2-Amino-5-(3-carboxyphenyl)pyrimidine; [1,1'-Biphenyl]-3-carboxylic acid, 2'-amino-5'-pyrimidinyl- (related); AI3-71499; BCP31989; ZINC000003869755
EINECS	Contact for details

Quality Control

Our 3-(2-Aminopyrimidin-5-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can be aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.