Description

Methyl 6-Methyl-4-(4-Methylbenzoyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyrimidine class of compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory applications.
• Agrochemical Research: Serves as a structural scaffold for developing new pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Material Science: Investigated for the development of specialty polymers and functional materials with specific optical or electronic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	Methyl 6-Methyl-4-(4-Methylbenzoyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	914349-17-0
Molecular Formula	C16H18N2O4
Molecular Weight	302.33 g/mol
Synonyms	Methyl 6-methyl-4-(4-methylbenzoyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbomethoxy-6-methyl-4-p-toluoyl-3,4-dihydropyrimidin-2(1H)-one; 4-(4-Methylbenzoyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester; 914349-17-0; 5-Methoxycarbonyl-6-methyl-4-p-toluoyl-1,4-dihydropyrimidin-2-one; DHPM derivative; Biginelli adduct; Tetrahydropyrimidine-5-carboxylate ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Methyl-4-(4-Methylbenzoyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.