Description

2-(Trifluoromethyl)Pyrimidine-4-Carboxamide is a high-value trifluoromethylated pyrimidine derivative, a key building block in modern synthetic chemistry. Its structure makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, catalysts, and functional materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tag in the design of chemical probes and enzyme inhibitors for biological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-(Trifluoromethyl)Pyrimidine-4-Carboxamide
CAS No.	914348-10-0
Molecular Formula	C6H4F3N3O
Molecular Weight	191.11 g/mol
Synonyms	2-(Trifluoromethyl)-4-pyrimidinecarboxamide; 4-Pyrimidinecarboxamide, 2-(trifluoromethyl)-; 2-Trifluoromethylpyrimidine-4-carboxylic acid amide; 2-(Trifluoromethyl)pyrimidine-4-carboxylic acid amide; Pyrimidine-4-carboxamide, 2-(trifluoromethyl)-; 914348-10-0; Amide of 2-(Trifluoromethyl)pyrimidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Pyrimidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.