Description

5-Bromo-2-(Piperidin-3-Yloxy)Pyrimidine is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrimidine-piperidine hybrid structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel, small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas. It is primarily utilized by R&D laboratories, process development chemists, and large-scale manufacturers within the global pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry R&D: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a starting material or intermediate in the development and scale-up of active pharmaceutical ingredient (API) manufacturing routes.
• Bioconjugation & Probe Development: The bromo and heterocyclic moieties make it suitable for creating chemical probes for biological target identification and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and development.

Basic Information

Product Name	5-Bromo-2-(Piperidin-3-Yloxy)Pyrimidine
CAS No.	914347-73-2
Molecular Formula	C9H12BrN3O
Molecular Weight	258.12 g/mol
Synonyms	5-Bromo-2-(3-piperidinyloxy)pyrimidine; 2-(Piperidin-3-yloxy)-5-bromopyrimidine; 5-Bromo-2-(piperidin-3-yloxy)pyrimidine; Pyrimidine, 5-bromo-2-(3-piperidinyloxy)-; 914347-73-2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Piperidin-3-Yloxy)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support customer audits and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.