Description

1-(5-Bromopyrimidin-2-yl)-4-piperidinone is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of kinase inhibitors and other small molecule drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile piperidinone-pyrimidine scaffold.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential intermediate for synthesizing organic electronic materials or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(5-Bromopyrimidin-2-yl)-4-piperidinone
CAS No.	914347-64-1
Molecular Formula	C9H10BrN3O
Molecular Weight	256.10 g/mol
Synonyms	4-Piperidinone, 1-(5-bromo-2-pyrimidinyl)-; 1-(5-Bromo-2-pyrimidinyl)piperidin-4-one; 1-(5-Bromopyrimidin-2-yl)piperidin-4-one; 1-(5-Bromo-pyrimidin-2-yl)-piperidin-4-one; 914347-64-1; AKOS025146064; 1-(5-bromopyrimidin-2-yl)piperidin-4-one; 1-(5-Bromopyrimidin-2-yl)-4-piperidone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyrimidin-2-yl)-4-piperidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.