Description

2-Amino-5-Bromo-4-Dimethoxymethylpyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidine ring structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. Pharmaceutical manufacturers and R&D laboratories need this material for developing next-generation therapeutic agents, where its specific bromo and amino functionalities enable precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analogs and other heterocyclic APIs targeting viral and oncological diseases.
• Antiviral Drug Development: Used in research and production of compounds designed to inhibit viral replication mechanisms.
• Anticancer Agent Synthesis: Serves as a building block for creating pyrimidine-based molecules that interfere with cancer cell proliferation.
• Agrochemical Research: Employed in the development of new fungicides and herbicides that leverage its heterocyclic core for biological activity.
• Chemical Biology & Proteomics: Utilized as a specialty reagent for labeling and modifying biomolecules in research settings.
• Material Science: Investigated as a monomer or additive for creating functional polymers with specific electronic or optical properties.

Basic Information

Product Name	2-Amino-5-Bromo-4-Dimethoxymethylpyrimidine
CAS No.	914347-52-7
Molecular Formula	C8H12BrN3O2
Molecular Weight	262.11 g/mol
Synonyms	4-(Dimethoxymethyl)-5-bromopyrimidin-2-amine; 5-Bromo-4-(dimethoxymethyl)-2-pyrimidinamine; 2-Pyrimidinamine, 5-bromo-4-(dimethoxymethyl)-; 5-Bromo-4-dimethoxymethyl-2-aminopyrimidine; 2-Amino-5-bromo-4-dimethoxymethyl-pyrimidine; 914347-52-7; 5-Bromo-2-amino-4-dimethoxymethylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-4-Dimethoxymethylpyrimidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production can align with cGMP guidelines for pharmaceutical applications upon request, ensuring reliable supply for your most critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.